A Novel High Resolution Positron Emission Tomography System for Measurement of Bone Metabolism

Abstract

The purpose of the work reported here is to develop high-resolution PET instrumentation for imaging the long bones. To-date a single plane prototype and a single plane second-generation instrumentation have been completed and evaluated. A generalized multi-planar detector element has also been designed and evaluated experimentally and a volumetric instrument has been designed through simulation studies. Radiopharmaceuticals for bone growth rate imaging have been developed for use in a demonstration study of imaging in a monkey osteoporosis model. Preliminary animal studies showing feasibility have been carried out.

Open PDF

Document Details

Document Type
Technical Report
Publication Date
Sep 01, 2003
Accession Number
ADA420885

Entities

People

  • John A. Correia

Organizations

  • Massachusetts General Hospital

Tags

Communities of Interest

  • Air Platforms
  • Biomedical
  • Energy and Power Technologies

DTIC Thesaurus Topics

  • Biomedical Research
  • Chemistry
  • Detection
  • Detectors
  • Diagnostic Imaging
  • Health Services
  • High Resolution
  • Imaging Techniques
  • Instrumentation
  • Measurement
  • Medical Personnel
  • Operating Systems
  • Positron Emission Tomography
  • Positron Emissions
  • Simulations
  • Tomography
  • Two Dimensional

Fields of Study

  • Physics

Readers

  • Immunology and Pathology
  • Medical Imaging.
  • Software Engineering