A Randomized Prospective Trial Comparing Paravertebral Block and General Anesthesia for Operative Treatment of Breast Cancer

Abstract

The goals of the study are to evaluate the role of paravertebral blocks regional anesthesia in patients undergoing operative treatment of breast cancer. Experience to date has shown that this anesthetic modality is safe and effective, and associated with excellent post operative pain control and minimization of nausea and vomiting associated with general anesthesia. Using a prospective randomized trial carried out at two institutions, we propose to measure quality of life variables including pain, postoperative nausea an vomiting, mood, and functional status in patients undergoing breast surgery with the traditional techniques of general anesthesia versus the region technique of paravertebral block. The preliminary phase of this trial, which establishes the safety and efficacy of performing the block technique, is complete. We are currently in the study portion of the trial and have consented and randomized a total of 35 patients at one institution thus far. Outcomes and study instruments are detailed in the report. Our collaborating institution, the Mayo Clinic Jacksonville, is awaiting final institutional approval in order to begin recruiting patients.

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Document Details

Document Type
Technical Report
Publication Date
Oct 01, 2003
Accession Number
ADA421016

Entities

People

  • Christina R. Weltz

Organizations

  • Icahn School of Medicine at Mount Sinai

Tags

Communities of Interest

  • Biomedical

DTIC Thesaurus Topics

  • Anesthesia
  • Breast Cancer
  • Cardiovascular Physiological Phenomena
  • Health Services
  • Institutional Review Board
  • Mastectomy
  • Medical Personnel
  • Neoplasms
  • Pain
  • Patient Care
  • Personnel Management
  • Physicians
  • Surgery

Fields of Study

  • Medicine

Readers

  • Cardiovascular Physiology
  • Clinical Trial Research.
  • Psychological Intervention/Treatment for Stress, Anxiety, PTSD, and Related Emotional and Cognitive Health Symptoms.