Proteolytic Mechanisms of Cell Death Following Traumatic Brain Injury
Abstract
In addition to being the leading cause of death for civilians under 45 years of age, recent studies have confirmed that traumatic brain injury (TBI) is also one of the most frequent causes of morbidity and mortality on the modem battlefield. Specifically, 40% of battlefield fatalities in the Viet Nam war were due to head wounds and it has been reported that, patients arriving alive at military field hospitals, 20% with extremely severe brain wounds die before surgery was performed, and 80% received neurosurgical treatment, with a 10% surgical mortality rate. Nearly half of all single and/or multiple wound combat deaths result from injuries to the head, and these injuries are among the most frequent cause of morbidity and mortality on the battlefield. Penetrating head injury alone accounts for 25% of all wartime casualties and approximately 40% of these injuries are fatal.
Document Details
- Document Type
- Technical Report
- Publication Date
- Oct 01, 2003
- Accession Number
- ADA421034
Entities
People
- Ronald L. Hayes
Organizations
- University of Florida