Monitoring Anthrax Vaccine Safety in US Military Service Members on Active Duty: Surveillance of Hospitalizations in Temporal Association with Immunization 1998

Abstract

We studied military medical hospitalizations for possible temporal associations with anthrax immunization in U.S. military personnel on active duty in 1998. Anthrax immunization, demographic, and hospitalization data were linked and analyzed using Cox proportional hazards modeling for hospitalization within 42 days of an anthrax vaccine dose. Discharge diagnoses were aggregated into 14 International Classification of Disease, Ninth Revision, Clinical Modification (ICD-9-CM) diagnostic categories. Approximately 11% of active-duty personnel received one or more doses of anthrax vaccine during 1998; those anthrax immunized were more likely to be younger and male. Lower hospitalization rates were observed in the anthrax- immunized, across doses and diagnostic categories. Adjusted risk ratios for hospitalization by diagnostic category suggests that anthrax-immunized active-duty service members were at equal or lesser risk of hospitalization than the nonimmunized.

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Document Details

Document Type
Technical Report
Publication Date
Jan 01, 2000
Accession Number
ADA421216

Entities

People

  • Linda Wang
  • Paul A. Sato
  • Robert John Reed
  • Tyler Clain Smith

Organizations

  • Naval Health Research Center

Tags

Communities of Interest

  • Biomedical

DTIC Thesaurus Topics

  • Abstracts
  • Active Duty
  • Classification
  • Data Analysis
  • Department Of Defense
  • Deployment
  • Diseases And Disorders
  • Governments
  • Health
  • Health Services
  • Medical Personnel
  • Military Medicine
  • Military Personnel
  • Monitoring
  • Skin Diseases
  • Surveillance
  • Vaccines

Fields of Study

  • Medicine

Readers

  • Infectious Disease/Epidemiology
  • Naval Personnel Management
  • Nuclear and Radiation Engineering.

Technology Areas

  • Biotechnology