Development of a Computer Decision Support System for Women With BRCA1 of BRCA2 Mutations
Abstract
The objectives of this study, "Development of a computer Decision Support System for Women with BRCA1 or BRCA2 Mutations" was to create a decision support system that provided individualized information about the expected benefits of alternative cancer risk reduction strategies for women with either a BRCA1 or BRCA2 mutation. The project was comprised of three phases: 1) development of the education booklet, 2) development of the Decision Support System (DSS), and 3) randomized controlled trial of the DSS. The primary outcome of the trial was decision satisfaction. Secondary outcomes included knowledge of the effects of alternative management options on cancer risk, anxiety and depression, and behavior and behavioral intentions. Women who were in the Decision Support System arm reported higher satisfaction with their decisions than did women in the control arm (mean Decision Satisfaction Score 31.2 vs. 26.2, p=O.O4). In addition, higher decision satisfaction at follow up was associated with cancer anxiety at baseline and having had breast cancer or a prophylactic mastectomy prior to enrollment. The results of this trial are currently being submitted for publication. In addition, we are currently developing a methodological review highlighting the ouestions raised by this trial and similar trials.
Document Details
- Document Type
- Technical Report
- Publication Date
- Aug 01, 2003
- Accession Number
- ADA421257
Entities
People
- Kartina Armstrong
Organizations
- University of Pennsylvania