Energy-and Intensity-Modulated Electron Beam for Breast Cancer Treatment

Abstract

In order to deliver MERT plans efficiently, we have designed and manufactured a prototype EMLC based on the results of Monte Carlo simulations and a Varian 25 x 25 Cm to the 2 electron applicator. The performance of the EMLC was experimentally evaluated and the results were compared with those of Monte Carlo simulations and a PMLC. We have also developed a complete system of Monte Carlo-based inverse treatment planning system for MERT plans. The system incorporates the Monte Carlo simulated electron pencil beams into the inverse planning process. Additionally, we have characterized the EMLC using a multiple-source beam model for fast Monte Carlo simulation, incorporated the EMLC into the EGS/BEAM simulations as an MLC component module, and created MERT plans for breast cancers. We have also studied the effect of beam delivery on optimized modulated electron radiation therapy plans in the final dose calculation. Furthermore, we have developed aperture-based MERT techniques for fast delivery of MERT plans. We believe that MERT provides a viable alternative modality to conventional Opposed tangential fields approach and photon IMRT.

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Document Details

Document Type
Technical Report
Publication Date
Oct 01, 2003
Accession Number
ADA421278

Entities

People

  • Arthur L. Boyer

Organizations

  • Stanford University

Tags

Communities of Interest

  • Biomedical
  • Energy and Power Technologies

DTIC Thesaurus Topics

  • Charged Particles
  • Computational Science
  • Computer Programming
  • Computer Programs
  • Computers
  • Electronic Mail
  • Electrons
  • Health Services
  • Ionizing Radiation
  • Linear Accelerators
  • Medical Personnel
  • Monte Carlo Method
  • Operating Systems
  • Radiation Oncology
  • Radiotherapy
  • Three Dimensional
  • Two Dimensional

Fields of Study

  • Medicine
  • Physics

Readers

  • Adaptive Control and Estimation with Uncertainty in Dynamic Systems.
  • Computational Modeling and Simulation
  • Medical Imaging.

Technology Areas

  • Directed Energy
  • Microelectronics