Intermittent Ultrasound Imaging of Prostate Cancer
Abstract
This study proposed to evaluate contrast-enhanced ultrasound imaging with a microbubble contrast agent in 300 subjects over a period of 3 years in order to improve the detection of prostate cancer. Although the grant period began 8/1/2001, patient recruitment actually commenced on 10/1/2001. Between 10/15/2001 and 7/31/2003 a total of 240 subjects provided informed consent. Laboratory blood tests (PSA) and ultrasound evaluations were completed on all 240 subjects (including the ultrasound interpretation worksheet of the primary reviewer). An independent blinded reader has completed review of the first 100 subjects. Pathological review for the presence and grade of &ancer has been completed for all 240 subjects. CD31 staining for micro-vessel density has been performed on the first 40 subjects. All available data has been entered into a computer database using an Excel spreadsheet. A preliminary analysis of the data from the first 201 subjects was incorporated into two abstracts that have been accepted for presentation at the 2003 annual meeting of the Radiological Society of North America (see appendix) . Based upon the current rate of recruitment we expect to reach the target goal of 300 subjects by February 2004.
Document Details
- Document Type
- Technical Report
- Publication Date
- Aug 01, 2003
- Accession Number
- ADA421352
Entities
People
- Ethan J. Halpern
Organizations
- Thomas Jefferson University