Skin Bioengineering: Noninvasive Transdermal Monitoring
Abstract
The long-term objective is to develop and optimize a novel, noninvasive iontophoretic approach for metabolic monitoring via the skin. The low-level current density drives both charged and highly polar (yet neutral) compounds across the skin at rates much greater than passive diffusion. As the skin offers a uniquely accessible body surface across which information can be extracted, we hypothesize that truly noninvasive and highly sensitive devices, which exploit uniquely paired flows of at least two substances, can be developed for iontophoretic monitoring applications. Proof-of-principle targets two analyses of significant interest; specifically, glucose, and lactate.
Document Details
- Document Type
- Technical Report
- Publication Date
- Jan 01, 2004
- Accession Number
- ADA421355
Entities
People
- Richard H. Guy
Organizations
- University of Geneva