Preliminary Investigation of the Role of Cellular Immunity in Estrous Cycle Modulation of Post-Resection Breast Cancer Spread

Abstract

It is hypothesized that the short term objectives of doing this proposal are to better understand which sex steroids and which cellular immune functions control post resection metastatic cancer spread. The long term goal is to use this understanding to develop testable hypotheses for "neoadjuvant" hormonal/immunological therapies, which when given at or around the time of a cancer resection, might result in diminishing the subsequent metastatic spread of the resected cancer. Progress has been made in each of the three technical directives and nine tasks, as outlined in the annual report.

Open PDF

Document Details

Document Type
Technical Report
Publication Date
May 01, 2003
Accession Number
ADA421466

Entities

People

  • William J. Hrushesky

Tags

DTIC Thesaurus Topics

  • Biological Rhythms
  • Blood
  • Blood Vessels
  • Breast Cancer
  • Cell Line
  • Cells
  • Chemistry
  • Culture Techniques
  • Data Analysis
  • Dna Microarrays
  • Gene Expression
  • Lymphocytes
  • Medical Personnel
  • Neoplasms
  • Proteins
  • Surgery
  • Tumor Cell Line

Fields of Study

  • Medicine

Readers

  • Oncology (Cancer Research).
  • Systems Analysis and Design