Assessing the Compatibility of Packed Red Blood Cells With Lactated Ringer's Solution
Abstract
Crystalloid solutions are frequently used to reconstitute packed red cells during rapid infusions during trauma situations and in the perioperative setting. Lactated Ringer Ys solution is a commonly used crystalloid for intravenous infusion. Calcium contained in lactated Ringer s solution has been reported to possibly cause blood clots because of replacing calcium ions previously chelated in the citrate anticoagulant. Authors of previous studies have cautioned against using lactated Ringer Ys solution to reconstitute packed red cells because of this calcium. Other studies have shown that there are no adverse effects when lactated Ringer Ys is used in situations when packed red cells are transfused rapidly. In this study, samples of CPD-preserved red cells were diluted with either lactated Ringer Ys solution or normal saline.
Document Details
- Document Type
- Technical Report
- Publication Date
- Oct 01, 1998
- Accession Number
- ADA421564
Entities
People
- Edward J. Helpling
Organizations
- Uniformed Services University of the Health Sciences