Prostate Specific Expression of Maspin in a Transgenic Mouse Model: Implications in Prostate Carcinogenesis
Abstract
The object of this proposal is to understand the tumor suppressor function of maspin in prostate, and to explore maspin's role in normal prostate development. Maspin transgenic mouse model will be employed to study the effects of maspin overexpression on mouse prostate tumorigenesis and metastasis. Prostatic tumorigenesis and normal prostate development will be studied using a variety of established techniques, including organ culture, histopathology, and molecular biology.
Document Details
- Document Type
- Technical Report
- Publication Date
- May 01, 2003
- Accession Number
- ADA421787
Entities
People
- Ming Zhang
- Zesheng Liu
Organizations
- Baylor College of Medicine