Dynamic Functional Mammoscopy: A Non-Ionizing Imaging Technique Enhancing Early Detection of Breast Cancer
Abstract
During the third and final year of this study, we focused on improving the imaging technology of Dynamic Functional Optical Mammoscopy (DFOM) and focused on technique on refining existing weaknesses in specificy identified during the second year of study. In addition, we summarize the case studies and analysis of data obtained during the first two years. This data included optical imaging of patients scheduled for biopsy of breast lesions. These patients were recommended for core or excisional breast biopsy on the basis of equivocal mammographic and ancillary clinical findings within ACR BI-RADS(TM) categories 3 or 4. Analysis of test results of 117 patients showed that DFOM modality detected cancer in 13 of the 15 patients in whom biopsies confirmed malignant lesions, giving a sensitivity of 87%. DFOM also correctly identified 79 of 102 benign lesions giving a specificity of 77%. In clinical practice, the adjunctive use of DFOM would have decreased the percentage of biopsies that turn out to be benign from 102/117 (87%) to 23/117 (20%). The negative predictive value, the chance that a negative DFOM result truly indicates a benign lesion, was 79/81(98%) for the cases included thus far. While encouraging, these results suggest the need for further patient studies on_specificity.
Document Details
- Document Type
- Technical Report
- Publication Date
- Apr 01, 2003
- Accession Number
- ADA421983
Entities
People
- Suzanne J. Smith
Organizations
- Columbia University