Integrated Cancer Research in Five Thematic Areas of Interest

Abstract

During the last Fiscal Year of the award, the Cancer Institute of Long Island benefited from CPMRP funding in a manner consistent with the proposed activities of the award. In the area of core instrumentation acquisition, the Applied Biosystems, Inc. Q-Star LC/MS/MS Mass Spectrometer that was acquired in Year 1 became fully operational and has supported research for 21 cancer investigators from 7 different departments. Data for several publications and new grants are being organized and the instrumentation is a widely accepted successful edition to the Cancer Proteomics initiative. Additionally, another research grade ABI MALDI-ToF was acquired, as well as preparatory robots to aid in spot excision and gel digestion. More recently, as specified in Year 2, much time was spent investigating and considering the best option for a 2-photon confocal microscope. Upon the conclusion of this process a Carl Zeiss Inc. Inverted Multi-Photon system was selected. The instrument is to be sited and operated in a class 100,000 clean room and located in a shared instrument facility contiguous to the cancer marker diagnostics laboratory as well as many other cancer research groups. The technology offers a new and exciting platform for cancer imaging and has been equipped to enable the imaging of living cells. Leading this project is the thematic program director, and now chair of the Department of Molecular Genetics and Microbiology, Dr. Dafna Bar-Sagi. A faculty member skilled in 2-Photon Microscopy will provide daily oversight for the instrument, and a PhD-level optical physicist will be recruited to operate the instrument. The instrument will be installed in September 2003. Consistent with the funding for this initiative was the granting of Research Support Units. These units serve to assist in the recruitment of new, well-trained cancer researchers. Each package provided support for laboratory personnel, small or specialized research equipment, and supplies.

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Document Details

Document Type
Technical Report
Publication Date
Jul 01, 2003
Accession Number
ADA423033

Entities

People

  • Craig C. Malbon

Organizations

  • State University of New York

Tags

DTIC Thesaurus Topics

  • Body Weight
  • Cancer
  • Chemistry
  • Confocal Microscopy
  • Genetics
  • Health Services
  • Instrumentation
  • Mass Spectrometry
  • Medical Personnel
  • Microscopes
  • Microscopy
  • Molecular Genetics
  • Neoplasms
  • Oncology
  • Prostate Cancer
  • Proteins
  • Proteomics

Readers

  • Defense Acquisition Program Management
  • Oncology and Biomarker-Based Cancer Detection.
  • Research Science/Academic Research

Technology Areas

  • AI & ML
  • AI & ML - DoD AI Strategy
  • Autonomy
  • Biotechnology