Optimized Hyperthermia Treatment of Prostate Cancer Using a Novel Intracavitary Ultrasound Array
Abstract
The eventual goal this research is to produce an ultrasound hyperthermia array which will uniformally heat the prostate to clinical temperatures for the treatment of prostate disease. This goal can be achieved by accounting for the physical differences between the prostate gland and surrounding tissue structures. It was therefore possible to design and construct as a transducer to produce uniform heating within the prostate while causing minimal damage to surrounding tissue. The second year of this three year research project was focused on the construction of the array based on our Year 1 results of computer simulations of the ultrasound energy interactions with the prostate. Three major areas accomplished during this term were: (a) transducer construction (b) optimization of the transducer array design, and (c) MRI thermometry experiments (in vitro and in vivo) using the hyperthermia ultrasound array. Specifically, a clinical applicator of the phased array has been constructed and is being used for MRI experiments. Additional information from the tissue modeling during Year 2 will be used to refine the heating pattern and can easily be incorporated in the current design. To summarize, there are no deviations from the original research plan and this research is progressing on schedule.
Document Details
- Document Type
- Technical Report
- Publication Date
- Jan 01, 2004
- Accession Number
- ADA423146
Entities
People
- Nadine B. Smith
Organizations
- Pennsylvania State University