Effects of Androgen Blockade on Cognitive Function and Quality of Life in Men with Prostate Cancer
Abstract
The purpose of this project is to examine the nature and severity of cognitive impairments experienced by men undergoing continuous androgen deprivation or intermittent androgen deprivation treatment. The cognitive abilities of androgen deprivation patients will be compared with those of a sample of healthy men. We are undertaking collection of data from three groups: 35 men on intermittent androgen deprivation therapy, 35 men on continuous androgen deprivation therapy, and an age- and education-matched sample of 35 healthy (cancer-free) men. Our major hypothesis is the patients undergoing androgen deprivation therapy will experience impairments in those cognitive abilities reported in the research literature to be related to androgen levels (e.g., spatial ability, working memory for visual information). There are as yet no results to report. During this second project year, we have begun data collection with androgen-deprivation subjects, but have continued to spend an inordinate amount of time in obtaining necessary institutional approvals.
Document Details
- Document Type
- Technical Report
- Publication Date
- Feb 01, 2004
- Accession Number
- ADA424095
Entities
People
- James P. Grigsby
Organizations
- University of Colorado Boulder