Physiological Stress Reactivity and Breast Cancer
Abstract
The objective of the present program of research is to study physiological processes that may mediate the links between psychological states and cancer. Specifically, the present study is designed to conduct an investigation of the cross-sectional associations between indices of stress reactivity and psychological coping styles in women with breast cancer and matched healthy controls. The aims of the project are: (1) to quantify parameters of biological reactivity to a behavioral stress paradigm in women with and without breast cancer; (2) To examine (a) group differences between women with and without breast cancer biological stress reactivity, and (b) the effects of menopause and familial risk on biological stress reactivity and emotional expression; and (3) To develop the methodology and obtain preliminary data which could justify subsequent, prospective research with high-risk populations. During the current reporting period, a new recruitment site has been added; 59 new subjects have been recruited in to the study; 51 assessments of research subjects have been completed; and preliminary (descriptive) analyses have been conducted on 35 subjects. The study relational database has been continuously updated, and biosamples have been stored at - 70 degrees C for assays.
Document Details
- Document Type
- Technical Report
- Publication Date
- Oct 01, 2003
- Accession Number
- ADA424210
Entities
People
- Pathik Wadhwa
Organizations
- University of California, Irvine