Continued Use of Zonisamide Following Development of Renal Calculi

Abstract

The reported incidence of renal calculi complicating Zonisamide (ZNS) therapy for epilepsy ranges from 0.2 to 4.4%(exp 1-3) Typically this complication leads to discontinuation of the drug. For patients uniquely responsive to Zonisamide, the benefits of continued treatment may outweigh the risk of calculus recurrence. We report three patients who developed nephrolithiasis but continued ZNS treatment without recurrence of calculi.

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Document Details

Document Type
Technical Report
Publication Date
Jul 15, 2004
Accession Number
ADA425098

Entities

People

  • Amit Verma
  • Karen C. Richards
  • Michael C. Smith

Organizations

  • Baylor College of Medicine

Tags

Communities of Interest

  • Biomedical

DTIC Thesaurus Topics

  • Acetazolamide
  • Air Force
  • Anticonvulsants
  • Calculi
  • Chemotherapy
  • Drug Abuse
  • Drug Addiction
  • Epilepsy
  • Kidney Diseases
  • Neurology
  • Pain
  • Therapy

Fields of Study

  • Medicine

Readers

  • Nanofabrication and Microfabrication.
  • Neurotrauma and Rehabilitation Medicine.
  • Systems Analysis and Design