Dietary Seaweed and Early Breast Cancer: A Randomized Trial

Abstract

The purpose of this research is to investigate whether eating brown seaweed (Undaria pinnatifida) can influence breast cancer risk. Brown seaweeds are popular in Japan, where the incidence of breast cancer is about 116 the rate of that reported for American women. In several animal studies of diet and cancer, adding seaweed to the normal diet resulted in longer healthy lives. In particular, we will examine cell-cell adhesion and gene expression associated with the consumption of dietary seaweeds by women who are healthy and women who have breast cancer. We will use commercially available seaweed. These seaweeds are commonly found in health food stores. To date, progress has been limited by the lack of approval from HSRRB (Proposal Log Number BC972552, HSRRB Log Number A-8050), with modifications. Modifications were submitted August 26, 2003. Final approval has not yet been granted. However, when this grant was first awarded in 1999 to the University of Massachusetts, we did a preliminary study to assess potential toxicity of dietary seaweed. The first paper on iodine content in commercially available seaweeds is now in press, and the second paper on bioavailability of seaweed iodine has been submitted for publication.

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Document Details

Document Type
Technical Report
Publication Date
May 01, 2004
Accession Number
ADA425639

Entities

People

  • Jane Teas

Organizations

  • University of South Carolina

Tags

DTIC Thesaurus Topics

  • Blood
  • Breast Cancer
  • Diseases And Disorders
  • Drug Therapy
  • Health Services
  • Lymphocytes
  • Meals
  • Medical Personnel
  • Neoplasms
  • Thyroid Diseases
  • United States
  • Vegetables

Readers

  • Technical Research and Report Writing.
  • Women's Health and Cancer Risk Research: African American Women and Pregnancy Outcomes.