A Multidisciplinary Evaluation of Mild Traumatic Brain Injury: Early Predictors of Outcome
Abstract
The purpose of this study is to identify a cohort of patients with mild Traumatic Brain Injury and follow them for 1 year post-injury to determine injury outcomes and identify factors that best predict long-term sequelae. The first year has been dedicated to finalization of study design and testing instruments, and logistical planning for this multi-disciplinary effort. Staff were hired and trained, and a manual of operations developed to standardize the protocols for evaluation components. A schedule for testing was developed, and enrollment criteria defined. Human subjects approval was obtained from both the University and Army review boards. Space was located within the Trauma Center for patient testing, and equipment moved and calibrated. A database was created for each of the evaluations, including a process for data back-up and migration. Laboratory protocols were developed for the collection, storage, and processing of blood samples for the S-100b tests. Actual recruitment began in October 2003. After an initial pilot phase it was determined that, although sufficient numbers of patients with mild TBI were admitted, a variety of issues have impacted recruitment. Based on this experience, protocol modifications are planned in order to correct the problem and enhance patient enrollment.
Document Details
- Document Type
- Technical Report
- Publication Date
- Apr 01, 2004
- Accession Number
- ADA425756
Entities
People
- Patricia Dischinger
Organizations
- University of Maryland, Baltimore