Biochemical Analysis of the BRCA2 Protein Complex
Abstract
This linked career development award and idea award (CDA part) aims at relieving my administrative duties to acquire molecular biology skills in biology research. I have learned all the molecular biology techniques in accordance to Task 1 and 2 as stated in the Statement of Work. I have also learned biochemistry and cell biology techniques including protein complex purification, indirect immuno-staining and functional assays for activation of the S-phase and 02/M checkpoints. This career development award has allowed me to finish the transition from a mass spectrometrist who concentrates on methodology development to a biologist who works on important problems that are related to breast cancer and other human disease. During the award period, I have published 5 papers as a corresponding author and many papers as a collaborator. I have obtained 3 RO1 grants from NIH to study the molecular mechanism of DNA damage checkpoint activation, which is important for suppression of breast cancer development.
Document Details
- Document Type
- Technical Report
- Publication Date
- Apr 01, 2004
- Accession Number
- ADA425776
Entities
People
- Jun Qin
Organizations
- Baylor College of Medicine