A Genomic Analysis of Anaerobic Aromatic Degradation

Abstract

The anaerobic degradation of aromatic compounds is important for environmental bioremediation because substantial amounts of toxic aromatic compounds are produced industrially and make their way into anoxic groundwaters and sediments. Although the biodegradation of aromatic compounds under anaerobic conditions has great practical significance, investigators have studied the degradation of only a very few different kinds of aromatics. In this era of microbial genomics it is now technically possible to take a comprehensive look at the complete biodegradation potential of an individual microbial species. The purple nonsulfur phototrophic bacterium Rhodopseudomonas palustris is an ideal organism for this. Its genome has recently been completely sequenced and it can be manipulated genetically. R. palustris also has great metabolic versatility and can grow on many different kinds of aromatic compounds. In the project period we have completed and published our description of the R. palustris genome sequence. We have completed a study of the lower pathway of benzoate degradation, characterized an enzyme involved in chloroaromatic degradation and initiated studies of the degradation of a green plant associated compound: 4-hydroxycinnamate.

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Document Details

Document Type
Technical Report
Publication Date
Jul 26, 2004
Accession Number
ADA426008

Entities

People

  • Caroline S. Harwood

Organizations

  • University of Iowa

Tags

DTIC Thesaurus Topics

  • Amino Acids
  • Aromatic Compounds
  • Bacteria
  • Benzoates
  • Biodegradation
  • Biotechnology
  • Degradation
  • Dna Microarrays
  • Fatty Acids
  • Genetics
  • Genome
  • Genomics
  • Microbial Genome
  • Microorganisms
  • Prokaryotes
  • Scientists
  • Sequences

Fields of Study

  • Biology
  • Environmental science

Readers

  • Analytical Chemistry
  • Groundwater Contamination Remediation.
  • Microbial Pathology

Technology Areas

  • Biotechnology
  • Biotechnology - Bioremediation