Targeting of Breast Tumors and Tumor Cells Using Inductive Magnetic Heating of Metallic Nanoparticles

Abstract

Our research in the first year has focused on the creation of nanoparticles designed for hyperthermic tumor ablation via magnetic field heating, and the development of equipment for genetic magnetic field generation. In the area of nanoparticle fabrication, we have changed our focus from metallic nanoparticles to superparamagnetic analogs. This change was made to avoid th high frequencies and energy fluxes required for metallic system . In our synthetic studies, we have developed particles that are stable and water soluble. In terms of equipment, we have discovered that the magnetic field generator described in the proposal was not powerful enough to obtain rapid heating of particles solutions. We are currently working with MSI industries to develop coils to be used with their 5 kW induction heating instrument.

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Document Details

Document Type
Technical Report
Publication Date
Jun 01, 2004
Accession Number
ADA426206

Entities

People

  • Vincent Rotello

Organizations

  • University of Massachusetts Amherst

Tags

Communities of Interest

  • Biomedical

DTIC Thesaurus Topics

  • Ablation
  • Biomedical Research
  • Breast Cancer
  • Culture Techniques
  • Fabrication
  • Frequency
  • Heating
  • Iron Oxides
  • Magnetic Fields
  • Metal Oxide Nanoparticles
  • Metallic Nanoparticles
  • Microparticles
  • Nanomaterials
  • Nanoparticles
  • Neoplasms
  • Particles
  • Targeting

Fields of Study

  • Physics

Readers

  • Nanocomposite Materials Science
  • Superconducting Magnet Technology
  • Thermal Physics or Thermal Science.

Technology Areas

  • Biotechnology
  • Biotechnology - Cancer Biotech