Interferon-Beta 1a and SARS Coronavirus Replication

Abstract

A global outbreak of severe acute respiratory syndrome (SARS) caused by a novel coronavirus began in March 2003. The rapid emergence of SARS and the substantial illness and death it caused have made it a critical public health issue. Because no effective treatments are available, an intensive effort is under way to identify and test promising antiviral drugs. Here, we report that recombinant human interferon-beta 1a potently inhibits SARS coronavirus replication in vitro.

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Document Details

Document Type
Technical Report
Publication Date
Feb 01, 2004
Accession Number
ADA426745

Entities

People

  • Christopher L. Karp
  • Elizabeth A. Fritz
  • John W. Huggins
  • Lisa Hensley
  • Peter B. Jahrling

Tags

Communities of Interest

  • Biomedical

DTIC Thesaurus Topics

  • Animal Diseases
  • Coronaviruses
  • Covid-19
  • Disease Outbreaks
  • Diseases And Disorders
  • Health
  • Health Services
  • Infection
  • Infectious Diseases
  • Interferon
  • Proteins
  • Public Health
  • Sars
  • Therapy
  • Virus Diseases
  • Viruses

Fields of Study

  • Biology
  • Medicine

Readers

  • Infectious Disease/Epidemiology
  • Naval Personnel Management