Biomolecular Computing by In Vitro Transcriptional Networks

Abstract

This grant supported the initial development of a novel biochemical system, in vitro transcriptional networks, that can be programmed to construct arbitrary circuits. These systems are a simplification of genetic regulatory networks. The foundational theory is completed; design, implementation, and characterization, and optimization of individual switches has been performed; and construction of non-trivial biochemical test circuits is still in progress.

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Document Details

Document Type
Technical Report
Publication Date
Apr 30, 2004
Accession Number
ADA426916

Entities

People

  • Erik Winfree
  • Jongmin Kim
  • Kristin Shantz
  • Sarina Mohanty
  • Shaun Lee

Organizations

  • California Institute of Technology

Tags

Communities of Interest

  • Materials and Manufacturing Processes

DTIC Thesaurus Topics

  • Abstracts
  • Carrier Proteins
  • Circuits
  • Computers
  • Construction
  • Information Processing
  • Networks
  • Neural Networks
  • Nucleic Acids
  • Optimization
  • Pattern Recognition
  • Ribonucleic Acids
  • Rna Stability
  • Steady State
  • Switches
  • Synthetic Biology
  • Template Patterns

Readers

  • Immunology
  • Integrated Circuit Design and Technology.
  • Mathematical Modeling and Probability Theory.

Technology Areas

  • Biotechnology