Anti-Angiogenic Gene Therapy for Prostate Cancer
Abstract
One of the major implications of prostate cancer progression is bone metastasis. Primary therapies for neoplastic prostate disease have been prostectomy followed by chemotherapy and radiation therapy. Although these forms of palliative therapies have been successful in early detected prostate cancers, a problem in majority of the treated cases is the growth of radiation/chemotherapy resistant tumor cells, which become refractory to treatment and exhibit an aggressive growth and metastatic profile. Thus, novel therapies that will control the process of recurrence and metastasis will have a profound clinical implication in the management of prostate cancer patients who undergo primary therapies.
Document Details
- Document Type
- Technical Report
- Publication Date
- Apr 01, 2004
- Accession Number
- ADA427170
Entities
People
- Selvarangan Ponnazhagan
Organizations
- University of Alabama