Molecular and Cellular Mechanisms of Possible Non-Thermal Biological Effect of Extremely High-Power Microwave Pulses

Abstract

This report results from a contract tasking UNESCO Chair Life Sciences International Educational Center as follows: At present the existence of extremely high-power microwave pulses (EHPP)-specific biological effects remains questionable, in part because of the difficulty in studying such effects in highly organized biological systems. The purpose of the proposed project is to find out whether there are EHPP-specific (non thermal) effects using a simple model less investigated in this aspect, i.e. on the metabolic mechanisms of the neuronal and muscle membrane. Taking into account that Na-K pump activity, Na:Ca exchange, intracellular cAMP, cGMP, cell hydration and membrane chemosensitivity all play a key role in metabolic regulation of cell function they would likely reflect any EHPP-specific effect. Therefore their characteristics will be studied before and after EHPP cell exposure. Results will provide data on basic mechanisms of EHPP effects and will also be applicable to evaluation and worldwide harmonization of safety standards.

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Document Details

Document Type
Technical Report
Publication Date
Sep 01, 2004
Accession Number
ADA428135

Entities

People

  • Sinerik N. Ayrapetyan

Tags

Communities of Interest

  • Biomedical
  • Energy and Power Technologies

DTIC Thesaurus Topics

  • Biological Sciences
  • Chemical Properties
  • Chemical Reactions
  • Computer Programs
  • Computers
  • Detectors
  • Electrical Conductivity
  • Electromagnetic Fields
  • Electromagnetic Radiation
  • Heat Capacity
  • High Power Microwaves
  • Hydration
  • Membrane Potentials
  • Microwaves
  • Neurons
  • Nucleotides
  • Standards

Readers

  • Academic Conference Management
  • Cellular and Molecular Pathways of Apoptosis.
  • Plasma Physics.

Technology Areas

  • Directed Energy