Endourethral MRI Guidance for Prostatic RF Ablation

Abstract

Prostate cancer constitutes a major health problem. Although the medical techniques currently in use to diagnose prostate cancer are successful, the methods to stage the cancer and visualize the invasion and spread of the cancer are inadequate. MRI is known to be the best method for staging but it does not offer image resolution that is acceptable, especially for detecting disease in the anterior prostate. In the first year of the project, we have developed a phased array coil setup that enabled us imaging of the prostate with 160 microns image resolution. The second year, we have developed a mechanical setup that enabled placement of the needles in the prostate with lmm accuracy. Both of these are published in high impact journals. Developed methods for imaging temperature changes in the prostate with high accuracy. In the third year, we applied the technique on patients in collaboration with investigators at NIH/NIC. We are seeking for a one-year No-Cost-Extension for completion of the last aim, i.e., precise RF ablation of the prostate.

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Document Details

Document Type
Technical Report
Publication Date
Jun 01, 2004
Accession Number
ADA428397

Entities

People

  • Ergin Atalar

Organizations

  • Johns Hopkins University

Tags

DTIC Thesaurus Topics

  • Ablation
  • Abstracts
  • Accuracy
  • Arrays
  • Biomedical Research
  • Climate Change
  • Computer Science
  • Guidance
  • High Resolution
  • Magnetic Resonance
  • Mechanical Properties
  • Phased Arrays
  • Prostate
  • Prostate Cancer
  • Prostheses And Implants
  • Standards
  • Therapy

Fields of Study

  • Medicine
  • Physics

Readers

  • Clinical Trial Research.
  • Oncology and Biomarker-Based Cancer Detection.
  • Systems Analysis and Design