PIAS Proteins in Androgen Signaling nd Prostate Cancer

Abstract

It has been well established that androgen receptor (AR) plays an important role in prostate cancer. Previous studies have suggested that the PIAS (protein inhibitor of activated STAT) family may be involved in the regulation of AR-mediated gene activation. The overall goal of this proposal is to study the role of PIAS proteins in androgen signaling and prostate tumor progression.

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Document Details

Document Type
Technical Report
Publication Date
Jun 01, 2004
Accession Number
ADA428522

Entities

People

  • Ke Shuai

Organizations

  • University of California, Los Angeles

Tags

DTIC Thesaurus Topics

  • Abstracts
  • Amino Acids
  • Androgen Receptors
  • Androgens
  • Biomedical Research
  • Cell Line
  • Cell Physiological Processes
  • Cells
  • Chemical Synthesis
  • Chemistry
  • Inhibition
  • Inhibitors
  • Neoplasms
  • Prostate
  • Prostate Cancer
  • Proteins
  • Transcription Factors

Fields of Study

  • Chemistry

Readers

  • Cellular and Molecular Pathways of Apoptosis.
  • Prostate Cancer Biology.