Macromolecular Design

Abstract

We produce unusual DNA motifs from synthetic oligonucleotides. We use these molecules individually or in combinations to produce systems to implement DNA nanotechnology. Computer optimization of DNA sequences is used to select the molecules to synthesize. Structures are assembled in solution, and 1D or 2D arrays are deposited on mica for characterization by AFM. 3D arrays are analyzed by X-ray diffraction. During the current project period, we have built a robust DNA nanomechanical device and a nanorobot that walks on a sidewalk. We have built robust 2D arrays, and have made large strides towards the control of matter in 3D.

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Document Details

Document Type
Technical Report
Publication Date
Dec 11, 2004
Accession Number
ADA428626

Entities

People

  • Nadrian C. Seeman

Organizations

  • New York University

Tags

Communities of Interest

  • Energy and Power Technologies

DTIC Thesaurus Topics

  • Chemistry
  • Crystal Structure
  • Dna Nanotechnology
  • Materials
  • Materials Science
  • Nanobiotechnology
  • Nanomaterials
  • Nanoparticles
  • Nanostructures
  • Nanotechnology
  • New York
  • Nucleic Acids
  • Polymers
  • Self Assembly
  • Three Dimensional
  • Two Dimensional
  • X-Ray Diffraction

Fields of Study

  • Chemistry

Readers

  • Integrated Circuit Design and Technology.
  • Molecular Genetics
  • Robotics and Automation.

Technology Areas

  • Biotechnology