Automatic Organ Localization for Adaptive Radiation Therapy for Prostate Cancer

Abstract

The focus of this study is adaptive radiation therapy (ART) for prostate cancer, in which the treatment is to be adjusted over time, based on CT images acquired on the treatment table before each daily treatment. The goals are twofold: We seek to make ART for prostate cancer possible, and we seek to evaluate how useful it will be. As steps toward making it possible, we have developed software tools to localize the areas to be targeted or avoided, and to evaluate the motion of the tissue from day to day. We have produced a tool called ImMap that can perform these tasks, and are beginning to study its reliability and effectiveness. To evaluate the utility of ART, we are using a data set consisting of repeated CT scans from approximately 20 treatment days for five anonymous cancer subjects, along with manual segmentations of the prostate, bladder, and rectum for each subject and each day. We have evaluated the motion of the body due to setup error, and are preparing to evaluate the motions of the organs with respect to the body.

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Document Details

Document Type
Technical Report
Publication Date
May 01, 2004
Accession Number
ADA428913

Entities

People

  • Brad Davis
  • Mark Foskey
  • Sarang C. Joshi

Organizations

  • University of North Carolina at Chapel Hill

Tags

DTIC Thesaurus Topics

  • Abstracts
  • Algorithms
  • Anatomy
  • Automatic
  • Biological Sciences
  • Biomedical Research
  • Computer Vision
  • Data Sets
  • Image Registration
  • Image Segmentation
  • Neoplasms
  • North Carolina
  • Prostate
  • Prostate Cancer
  • Radiation
  • Therapy
  • Tissues

Fields of Study

  • Medicine
  • Physics

Readers

  • Computer Vision.
  • Systems Analysis and Design
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