Breast Cancer Diagnosis Using Ultrasound and Diffusive Light

Abstract

We have developed a novel near-infrared optical technique with ultrasound localization. We have made significant progress on using our technique to improve breast cancer diagnosis. Initial results with a group of more than 90 biopsied patients have shown that early stage invasive cancers present two-fold greater total hemoglobin concentration than fibroadenomas and benign lesions. Initial results of advanced cancers have shown that the angiogenesis distributions of larger cancers are highly distorted and heterogeneous and the distributions correlate with histological microvessel density counts. We believe that our unique technique has a great potential to improve current practice on breast cancer diagnosis and to monitor tumor vascular changes of advanced cancers during the chemotherapy treatment.

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Document Details

Document Type
Technical Report
Publication Date
Aug 01, 2004
Accession Number
ADA429296

Entities

People

  • Quing Zhu

Organizations

  • University of Connecticut

Tags

Communities of Interest

  • Biomedical
  • Ground and Sea Platforms

DTIC Thesaurus Topics

  • Birds
  • Breast Cancer
  • Cancer
  • Carcinoma
  • Computational Science
  • Detection
  • Detectors
  • Diagnostic Imaging
  • Drug Therapy
  • Health Services
  • Medical Personnel
  • Neoplasms
  • Optical Detectors
  • Optical Properties
  • Three Dimensional
  • Two Dimensional

Fields of Study

  • Medicine

Readers

  • Aerosol Science/Aerosol Physics
  • Oncology (Cancer Research).
  • Oncology and Biomarker-Based Cancer Detection.