Beam Delivery Verification for Modulated Electron Radiation Therapy Treatment of Breast Cancer

Abstract

Aperture-based optimization is designed to reduce the complexity of Intensity Modulated Radiation Therapy (IMRT) treatment plans and is flexible enough to easily include delivery-related effects. In particular, aperture optimization requires no leaf sequencing and apertures are guaranteed to satisfy delivery constraints. It is therefore a promising alternative to beamlet-based IMRT. In this work, the authors considered a method of contour-based treatment planning in which, unlike in Direct Aperture Optimization (DAO), the aperture shapes are initially chosen to be the Beam Eye's View (BEV) of the target and the critical structures, and therefore are given as constants in the optimization process. The obvious advantage of this method with regard to DAO is that the only parameters that need be optimized are the fields' weights, and the plan is not optimized over all the possible aperture shapes. The authors' hope is that optimal aperture shapes are somewhat close to the BEV and that making this choice will save a significant amount of computation time.

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Document Details

Document Type
Technical Report
Publication Date
Aug 01, 2004
Accession Number
ADA430385

Entities

People

  • Arthur L. Boyer
  • Maxime Ponineau

Organizations

  • Stanford University

Tags

Communities of Interest

  • Energy and Power Technologies
  • Materials and Manufacturing Processes

DTIC Thesaurus Topics

  • Algorithms
  • Biomedical Research
  • Breast Cancer
  • Computations
  • Corpuscular Radiation
  • Electron Beams
  • Electronic Mail
  • Electrons
  • Genetic Algorithms
  • Geometry
  • Information Operations
  • Mathematical Analysis
  • Neoplasms
  • Optimization
  • Radiation
  • Therapy
  • Verification

Fields of Study

  • Physics

Readers

  • Medical Imaging.
  • Operations Research
  • Systems Analysis and Design

Technology Areas

  • Microelectronics