Radiation Dosimetry from Intratumoral Injection of Radionuclides in Human Breast Cancer

Abstract

This study has been designed to evaluation the spatial and temporal distribution as well as the radiation dosimetry of intratumoral injection of proprietary radiopharmaceuticals Ga-67 and Ga-68 Gallium Iron Macroaggregates (GIMA). Our team has adopted a 2-prong approach for this study. While the refinement of the human protocol is ongoing, we continue on the basic preparative studies to investigate the imaging methods as well as other radiopharmaceuticals and strategies for locoregional treatment. Our preliminary findings have led to presentation of 5 abstracts and filing of one non-provisional patent application. We are awaiting the final approval of the human protocol and will proceed with the human study once DOD approval of the human protocol is obtained. The integration of the 2-prong will likely lead to invaluable information about locoregional treatment of solid tumors and development of new treatment strategies.

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Document Details

Document Type
Technical Report
Publication Date
Jul 01, 2004
Accession Number
ADA430853

Entities

People

  • Franklin C. Wong

Organizations

  • The University of Texas MD Anderson Cancer Center

Tags

DTIC Thesaurus Topics

  • Anesthesia
  • Breast Cancer
  • Health Services
  • Ionizing Radiation
  • Law
  • Measurement
  • Medical Personnel
  • Neoplasms
  • Particles
  • Patent Applications
  • Physicians
  • Side Effects
  • Therapy

Fields of Study

  • Medicine

Readers

  • Clinical Trial Research.
  • Molecular and genetic basis of cancer.
  • Technical Research and Report Writing.

Technology Areas

  • Microelectronics