Metabolizing Enzyme 1 Polymorphisms and Prognosis Among Women Treated with Breast Cancer

Abstract

This study uses archived tissue and data to examine survival of women treated for breast cancer in relation to inherited polymorphisms of drug metabolizing enzymes. During year 3, we have completed review of over 750 potentially eligible cases and have collected tissue blocks for over 400, so that collection of tissue samples (SOW Task 2) is almost complete. We have obtained updated vital status and cause of death information for eligible subjects. An extension of the project into a fourth year has been approved. Laboratory assays to detect genotypes and tumor markers will be conducted during year 4. No reportable scientific results are available at the end of year 3.

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Document Details

Document Type
Technical Report
Publication Date
Oct 01, 2004
Accession Number
ADA431327

Entities

People

  • Carol Sweeney
  • Kristin E. Anderson

Organizations

  • University of Minnesota

Tags

DTIC Thesaurus Topics

  • Alkylating Agents
  • Biomedical Research
  • Breast Cancer
  • Buildings And Structures
  • Cancer
  • Data Analysis
  • Department Of Defense
  • Diseases And Disorders
  • Electronic Mail
  • Enzymes
  • Genotypes
  • Health Services
  • Hospitals
  • Lymph Nodes
  • Medical Personnel
  • Neoplasms
  • Pathology

Readers

  • Clinical Trial Research.
  • Molecular and genetic basis of cancer.
  • Women's Health and Cancer Risk Research: African American Women and Pregnancy Outcomes.