Reactive Topical Skin Protectant

Abstract

Biopraxis is developing a method for production of novel catalysts from inexpensive precursors, at high yield, under mild conditions. Under an earlier program, Biopraxis demonstrated that catalysts produced by this method can effectively neutralize the agent simulants diisopropyl fluorophosphate (DFP) and 2-chioroethyl ethyl sulfide (CEES). Government testing identified a formulation that exhibited excellent efficacy against both GD and HE), reducing nerve agent penetration by 93.1% and mustard penetration by 81.5% in comparison with the not reactive TSP. Accordingly, the Government awarded a follow-on program. The program was cut short due to funds being diverted for the Iraq war. The best formulation that had been identified by that time did not allow any detectable GD penetration in 2Ohours (99.96% reduction) and was projected to take more than 950 hours to reach breakthrough (a 16,502% increase). This same formulation also showed excellent efficacy against HD; i.e., a 217% increase in the time to breakthrough, and a 59% reduction in penetration by 2Ohours, in comparison with the non-reactive TSP. Since the catalysts are solid particulates, formulations may contain mixtures of catalysts that are superior for decontaminating different agents.

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Document Details

Document Type
Technical Report
Publication Date
Jun 01, 2004
Accession Number
ADA432035

Entities

People

  • Ann I. Grow

Tags

Communities of Interest

  • Biomedical

DTIC Thesaurus Topics

  • Biomedical Research
  • Catalysts
  • Chemical Warfare
  • Chemical Warfare Agents
  • Chemical Weapons
  • Electron Microscopy
  • Environmental Pollutants
  • Environmental Restoration And Remediation
  • Governments
  • Materials
  • Microscopes
  • Microscopy
  • Nerve Agents
  • Particles
  • Production
  • Production Engineering
  • War

Readers

  • Electrochemical Engineering/ Fuel Cell Technologies
  • Neurotoxicology
  • Polymer Science and Engineering.