Target Directed Drug Discovery: A Technology Driven Approach to Combating Malaria

Abstract

A procedure is described for identifying chemical entities with potential for being developed into antimalarial drugs. State-of-the-art technologies involving molecular genetics, computer modeling, structural analysis and high throughput screening have been leveraged to optimize the chances of success and minimize the time required.

Open PDF

Document Details

Document Type
Technical Report
Publication Date
Dec 01, 2004
Accession Number
ADA432101

Entities

People

  • A. Bhattacharjee
  • K. Kopydlowski
  • T. Hudson

Organizations

  • Walter Reed Army Institute of Research

Tags

Communities of Interest

  • Ground and Sea Platforms
  • Materials and Manufacturing Processes

DTIC Thesaurus Topics

  • Abstracts
  • Antimalarials
  • Biology
  • Blood Cells
  • Cells
  • Chemistry
  • Computer Programs
  • Computers
  • Erythrocytes
  • Genetics
  • Genomics
  • Malaria
  • Mathematical Models
  • Molecular Biology
  • Molecular Genetics
  • Spores
  • Structural Analysis

Fields of Study

  • Chemistry
  • Medicine

Readers

  • Molecular and genetic basis of cancer.
  • Parasitology and Pharmacology of Malaria.
  • Systems Analysis and Design

Technology Areas

  • Biotechnology
  • Biotechnology - Cancer Biotech