Bioeffects of Electromagnetic Nanopulses

Abstract

Theoretical analysis suggests that the nanopulse experiments we have carried our (typically 20kV/m for 1-4 h of exposure) do not cause sample heating. See Simicevic and Haynie (2005) The growth of E. coli is stimulated by exposure to nanopulses under moderate conditions - low electric field strength (10kV/m), low pulse frequency (<10 kHz), and 120 min of exposure. E. coli is inexpensive to culture and perhaps the simplest organism known to man. Moreover, it has been studied in considerable depth, making it valuable for experiments aimed at determining the mechanism of observed bioeffects of nanopulse exposure. The finding that the growth of this species of bacteria is enhanced on exposure is potentially of considerable value to biotechnology. See Ayenapurapu et al. The growth of a highly-malignant mouse mammary epithelial cell is stimulated by exposure to nanopulses under moderate conditions. These cells were chosen because they are a valuable model of apoptosis (programmed cell death) and are very familiar to Dr. Paul Sylvester, University of Louisiana at Monroe. The finding that these cells are stimulated on exposure is potentially of considerable value to tissue engineering. It could also be important for setting safety guidelines for exposure. This work is likely to result in at least one publication.

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Document Details

Document Type
Technical Report
Publication Date
Aug 01, 2004
Accession Number
ADA432195

Entities

People

  • Donald T. Haynie

Organizations

  • Louisiana Tech University

Tags

DTIC Thesaurus Topics

  • Apoptosis
  • Bacteria
  • Biotechnology
  • Cell Physiological Processes
  • Cells
  • Electric Fields
  • Electromagnetic Fields
  • Electromagnetic Pulses
  • Electromagnetic Radiation
  • Engineering
  • Epithelial Cells
  • Generators
  • Louisiana
  • Programmed Cell Death
  • Research Facilities
  • Tissue Engineering
  • Universities

Readers

  • Auditory Neuroscience/Auditory Physiology.
  • Cellular and Molecular Pathways of Apoptosis.
  • Microbial Pathology

Technology Areas

  • Biotechnology