Assessment of Lymphedema Risk Following Lymph Node Dissection and Radiation Therapy for Primary Breast Cancer

Abstract

The purpose of this study are two fold: 1) To determine the feasibility of using concurrent lymphoscintigraphy and CT imaging to identify lymph nodes critical for upper extremity drainage and to establish their relation to radiation therapy ports, and 2) To determine whether the irradiation of level I and II axillary lymph nodes critical for upper extremity drainage predicts the development of lymphedema. In addition to funding this research project, the Career Development award supports Dr. Cheville's completion of a Masters Degree in Clinical Epidemiology. This degree program will provide Dr. Cheville with the knowledge and skills required to succeed as an independent investigator. Dr. Cheville's masters' thesis, required for the degree, will involve data collection, analysis, and presentation of the lymphoscintigraphy study. To date, Dr. Cheville has completed half of the course work required for the Masters Degree, including extensive training in biostatistical analysis. Through consultation with Dr. Cheville's faculty mentor and course work in protocol development, the study design has been refined to address potential bias and confounding. With the support of faculty mentors in epidemiology and biostatistics, study subject enrollment and data collection have begun.

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Document Details

Document Type
Technical Report
Publication Date
Sep 01, 2004
Accession Number
ADA433048

Entities

People

  • Andrea L. Cheville

Organizations

  • University of Pennsylvania

Tags

DTIC Thesaurus Topics

  • Biostatistics
  • Breast Cancer
  • Data Analysis
  • Data Science
  • Databases
  • Diseases And Disorders
  • Epidemiology
  • Health
  • Information Science
  • Lymph Nodes
  • Lymphatic Diseases
  • Lymphatic System
  • Neoplasms
  • Radiation
  • Statistical Analysis
  • Test And Evaluation
  • Upper Extremity

Fields of Study

  • Medicine

Readers

  • Research Science/Academic Research
  • Women's Health and Cancer Risk Research: African American Women and Pregnancy Outcomes.