Engineering Antibodies to Detect Biological Warfare Agents

Abstract

Antibodies play a critical role in detecting biological warfare agents, as they possess exquisite specificity and sensitivity to their targets. Antibodies for military use must possess additional qualities. They must be robust in order to survive field conditions and shipping, must integrate into fielded equipment and must be produced quickly and cheaply. Recent advances in recombinant antibody technology provide the opportunity to produce cheaper detection antibodies, specifically engineered to improve their utility in a wide variety of detection platforms.

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Document Details

Document Type
Technical Report
Publication Date
Dec 01, 2004
Accession Number
ADA433211

Entities

People

  • B. C. Houghton
  • C. Mayers
  • N. A. Hopkins
  • S. A. Goodchild
  • T. E. Love
  • Vipul J. Patel

Organizations

  • Defence Science and Technology Laboratory

Tags

Communities of Interest

  • Materials and Manufacturing Processes

DTIC Thesaurus Topics

  • Abstracts
  • Antibodies
  • Bacteriophages
  • Biological Warfare
  • Biological Warfare Agents
  • Cell Line
  • Cells
  • Complex Mixtures
  • Culture Techniques
  • Detection
  • Molecules
  • Proteins
  • Sensitivity
  • Spores
  • Surface Plasmon Resonance
  • Surface Plasmons
  • Warfare

Readers

  • Economics
  • Systems Analysis and Design
  • Virology (or Medical Virology).