Development of a Fieldable, Rapid, Accurate and Sensitive Bio-Electronic, DNA Biosensor
Abstract
Integrated Nano-Technologies (INT) has developed novel electronic biosensor technology that will rapidly and accurately provide DNA-based field detection and identification of pathogenic organisms. The sensor is capable of detecting the binding of a single molecule of DNA or RNA and therefore does not require the use of PCR. The sensor chip can be engineered with an array of hundreds of independent test sites, which allows for confirmatory tests leading to a high level of specificity, the ability to screen for multiple threat agents simultaneously, and the capability to detect genetically engineered organisms. Biological agents continue to pose a major threat to U.S. troops as well as U.S. civilians both domestically and overseas. Rapid, accurate and sensitive detection and identification of biological agents is crucial to effective containment, neutralization and/or treatment. The U.S. military has an immediate need for a rapid, field deployable system for the detection and identification of biological agents, not only to protect military personnel from their effects, but also to contain and destroy them. An effective system must be: accurate, sensitive, rapid, easy to use, portable and field-ready. None of the currently available technologies meet all the necessary criteria.
Document Details
- Document Type
- Technical Report
- Publication Date
- Dec 01, 2004
- Accession Number
- ADA433463
Entities
People
- David Chafin
- Doyle Hill
- Michael Connolly