Development of a Web-Enabled Informatics Platform for Manipulation of Gene Expression Data

Abstract

High-throughput gene expression technologies such as Affymetrix and De Novo 2-Color Microarrays generate large scale measurements that require sophisticated bioinformatic platforms for data archival, management, integration, and analysis if researchers are to derive biologically meaningful relationships from the data. The Array Repository Data Analysis System (ARDAS 1.0) at Walter Reed Army Institute of Research is a web-enabled bioinformatic platform consisting of a Laboratory Information Management System (LIMS), an Analysis Information Management System (AIMS), and a Data Warehouse which coordinates activities of the system modules that allows queries across data within the system. The system, developed following successful Phase 1 and 2 SBIRs in conjunction with our commercial partner, 3rd Millennium, Inc, provides the foundation for an innovative enterprise-wide bioinformatics solution for US Army Medical Research and Materiel Command investigators seeking to leverage array technologies to develop vaccines and drugs against diseases and biothreat agents of military importance.

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Document Details

Document Type
Technical Report
Publication Date
Dec 01, 2004
Accession Number
ADA433520

Entities

People

  • Karen Kopydlowski
  • Roland Carel
  • Sheila A. Peel

Organizations

  • Walter Reed Army Institute of Research

Tags

Communities of Interest

  • Biomedical

DTIC Thesaurus Topics

  • Abstracts
  • Commerce
  • Computational Biology
  • Computer Programs
  • Data Analysis
  • Data Management
  • Databases
  • Department Of Defense
  • Experimental Design
  • Gene Expression
  • Language
  • Operating Systems
  • Platforms
  • Storage
  • User Interface
  • Warehouses
  • Web Browsers

Readers

  • Database Systems and Applications
  • Distributed Systems and Data Platform Development
  • Molecular Genetics

Technology Areas

  • Biotechnology