Genetic Risk of Breast Cancer Distress and Immune Response

Abstract

Based on Selye's framework of Physiological Response to Stress and Lazarus and Folkmans' Transactional Model of Stress (1984), the specific aims of this study are to: (1) examine the association of objective and subjective breast cancer risk with immune responses; (2) examine the mediating role of psychological distress on the relationship between subjective breast cancer risk and immune responses; (3) determine the moderating role of dispositional optimism on the relationship between subjective breast cancer risk and psychological distress; and (4) assess the association between objective and subjective breast cancer risk in 126 healthy women with (FH+) or without (FH-) family history of breast cancer in first-degree relatives (FDRs).

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Document Details

Document Type
Technical Report
Publication Date
Apr 01, 2005
Accession Number
ADA433879

Entities

People

  • Na-jin Park

Organizations

  • University of Alabama

Tags

DTIC Thesaurus Topics

  • Abstracts
  • Biomedical Research
  • Breast Cancer
  • Cancer
  • Cancer Screening
  • Carcinoma
  • Diseases And Disorders
  • Health
  • Health Care
  • Health Services
  • Materials
  • Medical Personnel
  • Neoplasms
  • Public Health
  • Risk
  • Risk Analysis
  • Risk Factors

Readers

  • Psychological Intervention/Treatment for Stress, Anxiety, PTSD, and Related Emotional and Cognitive Health Symptoms.
  • Women's Health and Cancer Risk Research: African American Women and Pregnancy Outcomes.

Technology Areas

  • Biotechnology