Optimized Hyperthermia Treatment of Prostate Cancer Using a Novel Intracavitary Ultrasound Array
Abstract
The goal of this research was to produce an ultrasound hyperthermia array which will uniformally heat the prostate to clinical temperatures for the treatment of prostate disease. This goal can be achieved by accounting for the physical differences between the prostate gland and surrounding tissue structures. Our Year 3 report describes major results from the simulations of a "Fresnel-lens-like" transducer of incoherent beams and ultrasound hyperthermia results of in vivo canine prostate using noninvasive magnetic resonance (MR) temperature monitoring. With the "Fresnel-lens-like" transducer, the novel idea of incoherent beams is helpful in reducing the complexity of the driving electronics with less control parameters to insure the uniformity and stability of the treatment. It was therefore possible to design and construct as a transducer to produce uniform heating within the prostate while causing minimal damage to surrounding tissue. Although there are no deviations from the original research plan, several final animals experiments will be conducted during a one-year no-cost extension period.
Document Details
- Document Type
- Technical Report
- Publication Date
- Jan 01, 2005
- Accession Number
- ADA434081
Entities
People
- Nadine Smith
Organizations
- Pennsylvania State University