The Many Faces of Meningococcal Disease: A Case Series and Review of Presentations and Treatment Options

Abstract

We present three cases of Neisseria meningitidis with varied clinical presentations, including meningococcemia, meningitis, and pneumonia. Our cases suggest an association between concomitant bacterial and viral infections, including group A streptococcus and adenovirus, and an increased risk of invasive Neisseria infections. Polymerase chain reaction data are a useful adjunct to bacterial cultures for the diagnosis. Our case series exemplify the continued high mortality of N. meningitides and highlights the need for more immunogenic vaccines for prevention.

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Document Details

Document Type
Technical Report
Publication Date
Jan 01, 2004
Accession Number
ADA434380

Entities

People

  • Braden R. Hale
  • Frank A. Chapman
  • Kevin L. Russell
  • Nancy F. Crum

Organizations

  • Naval Health Research Center

Tags

DTIC Thesaurus Topics

  • Anti-Bacterial Agents
  • Bacteria
  • Bacterial Infections
  • Blood
  • Cardiovascular Physiological Phenomena
  • Cardiovascular System
  • Cell Count
  • Chemical Synthesis
  • Chemistry
  • Diseases And Disorders
  • Health Services
  • Hematologic Diseases
  • Infection
  • Pain
  • Polymerase Chain Reaction
  • United States
  • Vaccines

Fields of Study

  • Medicine

Readers

  • Infectious Disease/Epidemiology
  • Systems Analysis and Design

Technology Areas

  • Biotechnology