Comparison of Image Quality Among Variations in Specimen Tissue Compression and Fluid Immersion for Diffraction Enhanced Imaging

Abstract

The current standard for breast cancer screening and diagnosis is screen-film mammography, which utilizes the principle of x-ray absorption to derive image contrast. A new imaging modality called Diffraction Enhanced Imaging (DEI) builds upon conventional x-ray imaging by adding two additional contrast mechanisms of refraction and scatter. Applications of this technique to breast imaging are promising, demonstrating significant improvements in visualization when compared digital mammography. One of the primary reasons for compressing the breast is to reduce the deleterious effects of x-ray scatter, reducing the total path through which the photon travels. This study seeks to investigate the effects of compression on breast tissue visualization using DEI. Results from this study will be applied to the development of a clinically based DEI system. Four tissues were imaged at different levels of compression using conventional mammography and DEI. A reader study will be used to determine the effect of compression on visualization.

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Document Details

Document Type
Technical Report
Publication Date
Jan 01, 2005
Accession Number
ADA434604

Entities

People

  • Christopher A. Parham

Organizations

  • University of North Carolina at Chapel Hill

Tags

Communities of Interest

  • Biomedical

DTIC Thesaurus Topics

  • Absorption
  • Breast Cancer
  • Cancer Screening
  • Compression
  • Contrast
  • Detectors
  • Diffraction
  • Health Services
  • Mammography
  • Medical Personnel
  • Neoplasms
  • North Carolina
  • Pilot Studies
  • Refraction
  • Standards
  • Visualizations
  • X Rays

Fields of Study

  • Medicine
  • Physics

Readers

  • Astronomy/Astrophysics
  • Image Processing and Computer Vision.
  • Oncology (Cancer Research).