Compact Positron Tomograph for Prostate Imaging

Abstract

The goal of this project is to construct a functioning compact positron tomograph, whose geometry is optimized for detecting prostate tumors with molecular tracers such as 11Ccholine (carbon-11 choline), in order to confirm the presence, absence or progression of prostate cancer. The camera consist of two banks of detectors mounted in a gantry. The bottom bank is fixed below the patient bed, and the top bank moves upward for patient access and downward for maximum sensitivity. The camera design was optimized, and extensive simulations were used to evaluate the expected camera performance. The camera was constructed. An iterative reconstruction algorithm was developed and tested with real data. Initial camera performance characterization was completed by imaging several phantoms with the system. Reconstructed images of extended and point source phantoms, using the completed camera in 3D-mode operation, demonstrate the feasibility of imaging prostate tumors with good spatial resolution and image contrast. The reconstruction algorithm will be fully optimized, the septa will be built and installed, and all NEMA phantom imaging will be completed by April, 2005.

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Document Details

Document Type
Technical Report
Publication Date
Jan 01, 2005
Accession Number
ADA434630

Entities

People

  • Jennifer S. Huber

Organizations

  • University of California, Berkeley

Tags

Communities of Interest

  • Advanced Electronics
  • Biomedical

DTIC Thesaurus Topics

  • Algorithms
  • Cancer
  • Data Acquisition
  • Detection
  • Detectors
  • Diagnostic Imaging
  • Geometry
  • Medical Personnel
  • Monte Carlo Method
  • Neoplasms
  • Positron Emission Tomography
  • Positron Emissions
  • Prostate Cancer
  • Simulations
  • Standards
  • Three Dimensional
  • Tomography

Fields of Study

  • Physics

Readers

  • Aerospace Test and Evaluation
  • Image Processing and Computer Vision.
  • Medical Imaging.