High Resolution Anatomic and Elastographic Transrectal Ultrasound for Improved Diagnosis of Prostate Cancer

Abstract

In this work we improve upon conventional Digital Rectal Examination (DRE) and PSA blood test by using ultrasound elasticity imaging. A latex sheath over the transrectal ultrasound probe is slightly inflated with water to provide a source of moderate pressure. The elasticity image is generated by cross-correlating successive raw radio frequency image data sets for incrementally increasing pressure Strain, and consequently elasticity, can be calculated from the displacement image. Our second objective is to use a new freehand 3D acquisition approach to obtain 3D image data sets. This approach uses a slightly modified transducer and an image motion tracking technique. Preliminary phantom based results are presented in this report. Excellent progress has been made with respect to the Statement of Work and first three of four total Specific Aims: A transducer has been specified and is on order. As promised, this transducer is designed to possess unsurpassed prostate scanning resolution by virtue of its exceptionally high frequency - up to 14 MHz. Prototype phantoms and complete ultrasound test instrumentation has been assembled. Preliminary ultrasound image speckle reduction work has been performed. Preliminary, dimensionally accurate, 3D prostate phantom images have been produced.

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Document Details

Document Type
Technical Report
Publication Date
Feb 01, 2005
Accession Number
ADA435037

Entities

People

  • John A. Hossack

Organizations

  • University of Virginia

Tags

Communities of Interest

  • Biomedical

DTIC Thesaurus Topics

  • Acquisition
  • Data Sets
  • Elastic Properties
  • Frequency
  • High Resolution
  • Image Processing
  • Instrumentation
  • Measurement
  • Motion Capture
  • Neoplasms
  • Pressure Distribution
  • Prostate
  • Prostate Cancer
  • Radio Frequency
  • Three Dimensional
  • Transducers
  • Ultrasounds

Fields of Study

  • Medicine
  • Physics

Readers

  • Medical Imaging.