Computerized Analysis and Detection of Missed Cancer in Screening Mammogram

Abstract

This project is to explore an innovative CAD strategy for improving early detection of breast cancer in screening mammograms by focusing on computerized analysis and detection of cancers missed by radiologists. The research in the second year is on (i) continuation of missed cancer analysis with a focus on density analysis and its effect on CAD detection; (ii) new CAD system design. The achievements include (1) A comprehensive analysis was taken on the effect of breast density on cancer detection. The accomplishments include breast dense tissue segmentation, correlation analysis of mammogram density features between missed and detected stages, statistical testing of density difference between normal and cancerous mammograms, baseline study of the effect of density on CAD detection performance using existing algorithm. (2) A new CAD system was designed based on the existing secondgeneration CAD algorithm and the missed cancer analysis. Due to the effective modification strategies taken in the new system, detection performance was improved for mammograms at both detected and missed stages. However, with the focus on missed cancer analysis and detection, a bigger improvement was obtained in detecting missed cases even though the general detection performance is still lower than that at detected stage.

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Document Details

Document Type
Technical Report
Publication Date
Apr 01, 2005
Accession Number
ADA435062

Entities

People

  • Lihua Li

Organizations

  • University of South Florida

Tags

Communities of Interest

  • Biomedical

DTIC Thesaurus Topics

  • Algorithms
  • Biomedical Research
  • Breast Cancer
  • Classification
  • Coefficients
  • Computer Vision
  • Correlation Analysis
  • Data Science
  • Databases
  • Detection
  • Identification
  • Information Processing
  • Information Science
  • Physicians
  • Statistical Algorithms
  • Statistical Analysis
  • Statistical Tests

Readers

  • Oncology and Biomarker-Based Cancer Detection.
  • Systems Analysis and Design