Cellular Effects of Enamel Matrix Derivative Are Associated With Specific Protein Components
Abstract
Emdogain (trademark) or enamel matrix derivative (EMD), is a preparation of matrix proteins derived from developing porcine teeth. Although EMD has been shown to enhance both soft tissue healing and regeneration of the periodontium, the mechanism of this action is still unknown. It is assumed, but not yet proven, that amelogenin, the most abundant protein in EMD, is the protein primarily responsible for the effects of EMD. The purpose of this study was to fractionate EMD and associate specific cellular effects with specific protein components.
Document Details
- Document Type
- Technical Report
- Publication Date
- May 01, 2005
- Accession Number
- ADA435300
Entities
People
- Dwight L. Johnson
Organizations
- Air Force Institute of Technology