Plastic-Based Structurally Programmable Microfluidic Biochips for Clinical Diagnostics

Abstract

The objective of this project is to develop a smart disposable polymer lab-on-a-chip for clinical diagnostics and point-of-care testing, which has the sampling/identifying capability of fast and reliable measurements of metabolic parameters from a human body with minimum invasion. The fully integrated disposable biochip is capable of precise volume control with smart microfluidic manipulation without costly on-chip microfluidic components. The biochip has a unique power source using on-chip pressurized air reservoirs, for microfluidic manipulation, avoiding the need for complex microfluidic pumps. Through the project, an innovative, fully integrated, plastic microfluidic lab-on-a-chip has been successfully developed and characterized for the dual applications of a stand-alone smart disposable polymer lab-on-a-chip as well as a wrist watch-type blood analyzer.

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Document Details

Document Type
Technical Report
Publication Date
May 01, 2005
Accession Number
ADA435658

Entities

People

  • Chong H. Ahn
  • Gregory Beaucage
  • Joseph H. Nevin

Organizations

  • University of Cincinnati

Tags

Communities of Interest

  • Biomedical
  • Energy and Power Technologies
  • Sensors

DTIC Thesaurus Topics

  • Application-Specific Integrated Circuits
  • Bipolar Junction Transistors
  • Chemical Synthesis
  • Chemistry
  • Computational Fluid Dynamics
  • Energy Consumption
  • Fabrication
  • Fluids
  • Health Services
  • Manufacturing
  • Mass Production
  • Materials Science
  • Microelectromechanical Systems
  • Protein Microarrays
  • Resins
  • Surface Properties
  • Transducers

Fields of Study

  • Chemistry

Readers

  • Materials Science
  • Nanocomposite Materials Science
  • Nanoscale Plasmonic Nanotechnology